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| # | Lag | M | V | F | +/- | P | |
|---|---|---|---|---|---|---|---|
| Eastern Conference | |||||||
| 1 | Philadelphia Union | 17 | 10 | 3 | 14 | 34 | |
| 2 | FC Cincinnati | 17 | 9 | 5 | 1 | 30 | |
| 3 | Inter Miami CF | 16 | 8 | 3 | 9 | 29 | |
| 4 | Nashville SC | 17 | 8 | 4 | 9 | 29 | |
| 5 | Columbus Crew | 17 | 7 | 3 | 3 | 28 | |
| 6 | New York Red Bulls | 17 | 8 | 6 | 9 | 27 | |
| 7 | Orlando City SC | 17 | 7 | 4 | 9 | 27 | |
| 8 | Charlotte FC | 17 | 8 | 8 | 1 | 25 | |
| 9 | New York City | 17 | 7 | 6 | 0 | 25 | |
| 10 | New England Revolution | 15 | 6 | 4 | 5 | 23 | |
| 11 | Chicago Fire | 15 | 6 | 5 | 0 | 22 | |
| 12 | D.C. United | 17 | 4 | 7 | -13 | 18 | |
| 13 | Atlanta United FC | 17 | 4 | 8 | -9 | 17 | |
| 14 | Toronto FC | 17 | 3 | 10 | -6 | 13 | |
| 15 | CF Montreal | 17 | 1 | 11 | -20 | 8 | |
| Western Conference | |||||||
| 1 | Vancouver Whitecaps FC | 15 | 9 | 1 | 15 | 32 | |
| 2 | San Diego | 17 | 9 | 5 | 11 | 30 | |
| 3 | Minnesota United FC | 17 | 8 | 3 | 10 | 30 | |
| 4 | Seattle Sounders | 17 | 7 | 5 | 3 | 26 | |
| 5 | Portland Timbers | 16 | 7 | 4 | 3 | 26 | |
| 6 | Los Angeles | 15 | 6 | 4 | 5 | 23 | |
| 7 | San Jose Earthquakes | 17 | 6 | 7 | 6 | 22 | |
| 8 | Colorado Rapids | 16 | 6 | 6 | -4 | 22 | |
| 9 | Houston Dynamo | 17 | 5 | 7 | -3 | 20 | |
| 10 | Austin | 17 | 5 | 7 | -9 | 20 | |
| 11 | FC Dallas | 16 | 4 | 6 | -8 | 18 | |
| 12 | Sporting KC | 16 | 4 | 8 | -3 | 16 | |
| 13 | Real Salt Lake | 17 | 4 | 10 | -9 | 15 | |
| 14 | Saint Louis City SC | 16 | 3 | 8 | -8 | 14 | |
| 15 | Los Angeles Galaxy | 17 | 1 | 12 | -21 | 7 | |
M = Matcher
V = Vinster
F = Förluster
+/- = Målskillnad
P = Poäng